This randomized trial evaluates the efficacy and safety of losmapimod vs placebo on cardiovascular outcomes in patients hospitalized with an acute myocardial infarction (MI).
This cross-sectional study compares mortality and readmission rates for acute myocardial infarction, heart failure, and pnemonia among older men treated at VA and non-VA hospitals in urban metropolitan statistical areas.
This Rational Clinical Examination examines the accuracy of initial history, physical examination, electrocardiogram, and risk scores combined with the first cardiac-specific troponin for diagnosing acute coronary syndrome in the emergency department.
This cohort study uses registry and Medicare claims data to assess the frequency of ICD implantation within 1 year of myocardial infarction and to compare mortality in patients with vs without ICDs.
This randomized superiority trial in China found that among patients undergoing PCI, bivalirudin was associated with reduced adverse effects compared with heparin alone and heparin plus tirofiban.
This retrospective pooled analysis of 8 clinical trials reports that obstructive non–infarct-related artery disease was common among patients presenting with ST-elevation myocardial infarction (STEMI).
In a retrospective cohort study of veterans with diabetes initially treated with metformin, Roumie and coauthors compared time to acute myocardial infarction, stroke, or death in patients who added insulin or a sulfonylurea.
Lexis and coauthors conducted a double-blind, placebo-controlled trial in 380 Dutch patients to evaluate the effect of metformin treatment on preservation of left ventricular function in patients without diabetes presenting with ST-segment elevation acute myocardial infarction (AMI).
Carrero and coauthors study outcomes associated with warfarin treatment in relation to kidney function among 24 317 patients after myocardial infarction (MI) in Sweden from 2003 to 2010. In an Editorial, Winkelmayer discusses whether these findings should change clinical practice in caring for patients with atrial fibrillation worldwide.