Thom and coauthors conducted a randomized trial of 2004 participants in India and Europe with or at high risk of established cardiovascular disease (CVD) to assess whether a fixed-dose combination of aspirin, statin, and 2 antihypertensive agents vs usual care improved adherence to therapy and 2 major CVD risk factors. Gaziano comments in an editorial.
A 67-year-old man with a history of heavy smoking and alcohol consumption presented with painless vesicles and milia on the dorsal surfaces of the hands. Results of a basic laboratory tests were normal; liver function tests revealed elevated levels of bilirubin, AST, and ALT. What would you do next?
A 76-year-old man recently diagnosed with type 2 diabetes and a history of hypertension requested assistance with managing his type 2 diabetes. His fingerstick blood glucose diary showed consistent recordings of greater than 350 mg/dL and his hemoglobin level was 13.3 g/dL. How do you interpret these test results?
A 64-year-old man with type 2 diabetes and hypertension has begun to experience generalized weakness. His laboratory results show a serum potassium level of 6.6 mEq/L (reference range, 3.5-5.0). How do you interpret the results?
A 53-year-old man with chest pain and treated hypertension undergoes an exercise treadmill test, which demonstrates 1.5-mm ST-segment depression in inferolateral leads during recovery. How do you interpret the test result?
This pharmacoepidemiology study uses NHANES data to describe trends in prescription drug use among US adults between 1999 and 2012.
This Medical Letter on Drugs and Therapeutics article provides information about sacubitril/valsartan, a recently approved fixed-dose combination medication for patients with heart failure and reduced ejection fraction.
A 67-year-old woman presented with fatigue for 4 weeks; a history of type 2 diabetes mellitus, hypertension, hyperlipidemia, and allergic rhinitis; and leukocytosis with predominant granulocytes. What’s the diagnosis?
This review summarizes approaches to managing hypertension in octogenarians based on guidelines of international expert organizations.