This meta-analysis of trials comparing treatment of acute ischemic stroke with vs without endovascular thrombectomy characterizes the threshold time after which treatment is no longer beneficial.
This JAMA Clinical Guidelines Synopsis summarizes the American Heart Association/American Stroke Association (AHA/ASA) 2014 guidelines on primary prevention of stroke.
In this Viewpoint, CDC Director Thomas Frieden advocates for proposed FDA guidelines that set targets for the reduction of sodium in the US food supply.
This study uses data from a trial comparing clopidogrel and aspirin vs aspirin alone for preventing stroke in patients with TIA to investigate associations between CYP2C19 status and effects of the drugs.
This study uses risk scores from 2 studies to assess their accuracy in predicting cardiovascular events among patients with stable coronary heart disease.
This randomized trial assesses the efficacy of a structured, task-oriented motor training program vs usual and customary occupational therapy for patients with stroke with upper extremity motor deficits.
This Viewpoint proposes widespread screening for atrial fibrillation using accessible and inexpensive means as a public health intervention for preventing stroke.
This cohort study assessed the accuracy of the CHA2DS2-VASc score for predicting ischemic stroke, thromboembolism, and death in patients with heart failure with and without atrial fibrillation.
This prospective cohort study reports that incident stroke among participants aged 45 years or older without cognitive impairment was associated with acute decline in cognitive function and also accelerated and persistent cognitive decline over 6 years.
This systematic review summarizes the pathophysiology of acute brain ischemia and infarction and available reperfusion treatments.
This randomized, double-blind clinical trial found that among adults with hypertension in China without a history of stroke or myocardial infarction, the combined use of enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke.
This randomized controlled trial compares use of a balloon-expandable stent vs medical therapy in patients with symptomatic intracranial arterial stenosis.
In this follow-up study of a US registry of patients undergoing transcatheter aortic valve replacement, 1-year outcomes included overall mortality of 23.7%, stroke rate of 4.1%, and a composite of death and stroke of 26.0%.