This randomized trial compares the immunogenicity and safety of avian influenza A(H7N9) vaccines that differ by adjuvant type and dosing schedule.
This randomized trial reports that receipt of a single dose of influenza A(H5N1) vaccine was associated with sufficient immunologic priming to facilitate response to a different H5N1 antigen using a low dose of booster vaccine; in participants not previously vaccinated, low-dose vaccine plus adjuvant was more immunogenic compared with higher doses of unadjuvanted vaccine.
This Medical News feature discusses the progress and challenges in HIV/AIDS treatement and research highlighted by the 2016 International AIDS conference in Durban, South Africa.
This commentary by JAMA Oncology Editor Mary L. Disis, MD, outlines advances in oncology through the laboratory discoveries and clinical research by Lasker Award recipients over the last 65 years.
In this Viewpoint, Allison discusses discoveries involving regulation of the T-cell response, development of immune checkpoint blockade in cancer therapy, and implications of engaging the immune response as a new modality for cancer treatment.
This Editorial discusses the need for interventions for primary prevention of type 1 diabetes in children at genetically high risk.
Bezerra and coauthors report on the effect of high-dose corticosteroids following hepatoportoenterostomy on bile drainage in infants with biliary atresia.
Omuro and DeAngelis review the clinical management of malignant gliomas, including genetic and environmental risk factors such as cell phones, diagnostic pitfalls, symptom management, specific antitumor therapy, and common complications.