This study compares the ability of an HIV antigen/antibody combination assay to detect acute HIV infection vs pooled HIV RNA testing in patients with a negative result for the rapid HIV test.
This randomized clinical trial compares the effect of patient navigation (care coordination) with or without financial incentives with usual care on viral suppression and death among hospitalized patients with HIV infection and substance use.
This statement from the International Antiviral Society–USA updates recommendations for the use of antiretroviral drugs (ARVs) to treat adults with established HIV infection and to prevent HIV infection among persons at risk of infection.
This cohort study describes the role of within-couple HIV transmission among serodifferent couples having condomless sex while the HIV-positive partner was using suppressive antiretroviral therapy.
Wood and colleagues assessed the accuracy of symptoms and signs of early HIV infection in an analysis of data from 16 studies (24 745 adult patients). They found that genital ulcers, weight loss, vomiting, and swollen lymph nodes were associated with early HIV infection; however, these findings had limited utility to detect or rule out HIV infection.
In a cluster randomized trial conducted in Blantyre, Malawi, MacPherson and coauthors investigated whether offering optional home initiation of HIV care after HIV self-testing might increase demand for antiretroviral therapy initiation, compared with HIV self-testing accompanied by facility-based services only.
In the AWARE randomized clinical trial, Metsch and coauthors assessed the effect of brief patient-centered risk-reduction counseling at the time of a rapid HIV test on the subsequent acquisition of sexually transmitted infections. In an Editorial, Haukoos and Thrun discuss the elimination of prevention counseling from HIV screening.
This randomized trial reports high rates of sustained virologic response in the first part of a open-label study of ombitasvir, paritaprevir (co-dosed with ritonavir), and dasabuvir with ribavirin for 63 patients with hepatitis C virus genotype 1 and human immunodeficiency virus 1 co-infection.
This pilot study reports high rates of posttreatment sustained virologic response after use of combined ledipasvir and sofosbuvir among patients co-infected with hepatitis C virus genotype 1 and human immunodeficiency virus.