Dr Mathurin and coauthors determined whether the addition of pentoxifylline to prednisolone is more effective than prednisolone alone in 270 patients with severe alcoholic hepatitis. In an accompanying editorial, Drs Halegoua-De Marzio and Fenkel discuss the efficacy of the use of pentoxifylline.
This Medical News article discusses recent efforts by the Department of Veterans Affairs to extend new hepatitis C treatments to all veterans within its health care system.
A 56-year-old man with longstanding human immunodeficiency virus (HIV) infection presented with new-onset fatigue and malaise, fever, and a macular rash involving the palms and soles. What is the diagnosis?
This open-label uncontrolled study of patients with chronic HCV genotype 1 infection and cirrhosis reports high rates of SVR12 in those who received a 12-week oral fixed-dose regimen of daclatasvir, asunaprevir, and beclabuvir, with or without ribavirin.
Jonas and coauthors conducted a systematic review and meta-analysis of the benefits and harms of medications for adults with alcohol use disorders that included 122 randomized clinical trials and 1 cohort study (22 803 participants). In an Editorial, Bradley and Kivlahan discuss the importance of patient-centered care and shared decision making for patients with alcohol use disorders.
Foa and coauthors report on concurrent naltrexone and prolonged exposure therapy for patients with comorbid alcohol dependence and posttraumatic stress disorder. In an accompanying Editorial, Mills discusses treatment of comorbid substance dependence and posttraumatic stress disorder.