This randomized clinical trial investigates whether cardiovascular magnetic resonance–guided care is superior to National Institute for Health and Care Excellence guidelines–directed care and myocardial perfusion scintigraphy–guided care in reducing the occurrence of unnecessary angiography among patients with suspected coronary heart disease.
This study uses risk scores from 2 studies to assess their accuracy in predicting cardiovascular events among patients with stable coronary heart disease.
This cohort study assesses whether rotating night shift work is associated with risk of coronary heart disease (CHD) over 24 years of follow-up among women in the Nurses’ Health Studies.
This randomized trial reports that among men with coronary heart disease, use of a lifestyle-focused text messaging service vs usual care resulted in modest improvement in low-density lipoprotein cholesterol levels and greater improvement in other cardiovascular disease risk factors.
This systematic review and meta-analysis assesses the association between several means of blood pressure–lowering treatment and vascular disease in patients with diabetes.
This randomized clinical trial reports that use of coronary computed tomography angiography to screen for coronary artery disease is not supported among asymptomatic patients with type 1 or type 2 diabetes.
This retrospective pooled analysis of 8 clinical trials reports that obstructive non–infarct-related artery disease was common among patients presenting with ST-elevation myocardial infarction (STEMI).
This randomized clinical trial of 4524 patients undergoing transfemoral coronary angiography reports that vascular closure devices were noninferior to manual compression in terms of vascular access-site complications and reduced time to hemostasis.
This retrospective observational analysis of ST-elevation myocardial infarctions (STEMIs) from a California database found that patients who had a STEMI while hospitalized for a non–acute coronary syndrome condition were less likely to undergo invasive testing or intervention and had a higher in-hospital mortality rate than those with outpatient onset of STEMI.
In a multicenter, prospective, observational trial at 6 US sites, Criqui and colleagues study a diverse cohort of 3398 men and women, aged 45 to 84 years, to determine the independent associations of coronary artery calcium (CAC) volume and CAC density with incident cardiovascular disease events. In a related Editorial, Greenland discusses more evidence for CAC as a measure of cardiovascular risk.
Nicholls and coauthors report the results from the randomized clinical Aliskiren Quantitative Atherosclerosis Regression Intravascular Ultrasound Study (AQUARIUS). In an accompanying Editorial, Tardiff and Grégoire discuss renin-angiotensin system inhibition and secondary cardiovascular prevention.
To identify genetic determinants of coronary heart disease (CHD) that are specific to diabetic patients, Qi and coauthors studied 5 independent sets of CHD cases and non-CHD controls to identify genetic variants related to metabolism.
Gutiérrez and coauthors examine whether the association of urinary albumin excretion with coronary heart disease (CHD) events differs by race in a prospective cohort study of 28 207 black and white US adults (aged ≥45 years) enrolled 2003-2007 with follow-up through December 31, 2009. Winkelmayer and Weiner provide comment in the related Editorial.
Ferraro and coauthors examine the association between a history of kidney stones and the risk of coronary heart disease in 3 large prospective cohorts of US participants.
Robinson-Cohen and coauthors examine the association of serum 25-hydroxyvitamin D concentration with risk of coronary heart disease in a multiethnic population. In an Editorial, Norris discusses important insights for further research into the complex relationships among race/ethnicity, vitamin D, and coronary heart disease.