This population epidemiology study uses UK clinical database data to investigate trends in prevalence of cardiovascular risk factors and management strategies and their association with trends in mortality among patients with non–ST-elevation myocardial infarction (NSTEMI) between 2003 and 2013.
A man in his 70s with a history of recent CABG surgery presented with blue, tender plantar macules on several toes and red, tender macules on his hands. Laboratory findings included a BUN level of 70 mg/dL, serum creatinine level of 6.1 mg/dL, and peripheral eosinophilia. What would you do next?
This randomized clinical trial compares the effects of short-term high-dose perioperative atorvastatin vs placebo on acute kidney injury following cardiac surgery.
Garg and coauthors report on a kidney function substudy of patients who participated in the Coronary Artery Bypass Grafting Surgery Off- or On-pump Revascularisation Study (CORONARY) to assess kidney function after off-pump or on-pump coronary artery bypass graft surgery.
To summarize the current evidence comparing the effectiveness of CABG surgery and PCI in patients with unprotected left main disease, multivessel coronary artery disease, diabetes, or left ventricular dysfunction, Deb and coauthors evaluated 13 randomized clinical trials and 5 meta-analyses.
In an analysis of data from 369 226 Medicare beneficiaries who underwent aortic valve replacement between 1999 and 2011, Barreto-Filho and coauthors examined trends in procedure rates, the association with coronary artery bypass graft surgery, and patient outcomes.
Cohen and colleagues compare the effect of coronary artery bypass graft surgery vs percutaneous coronary intervention using drug-eluting stents on health status among 1880 patients with diabetes mellitus and multivessel coronary artery disease between 2005 and 2010.
To investigate how different financial incentives between Medicare Advantage and Medicare fee-for-service reimbursement structures influence cardiovascular procedure use, Matlock and coauthors studied rates of coronary angiography, percutaneous coronary intervention, and bypass surgery in nearly 6 million Medicare beneficiaries. Krumholz provides comment in the related Editorial.