This observational study found no association between hospital-based participation in the National Surgical Quality Improvement Program and improvements in postoperative outcomes over time in patients undergoing elective operations at US academic hospitals.
Iranmanesh and colleagues assess surgical treatment options for patients at intermediate risk of a common duct stone in a randomized clinical trial and 6-month follow-up of 100 patients in a Geneva, Switzerland hospital, June 2011-February 2013.
To determine whether antibiotic treatment before and after cholecystectomy, the FRENCH Study group randomized 414 patients between May 2010 and August 2013 with acute calculous cholecystitis to receive either no antibiotic treatment after surgery or amoxicillin plus clavulanic acid for 5 days after surgery. They found that number of infections did not differ between groups.
In a clinical trial involving 214 patients who had disabling pain after cholecystectomy, Cotton an coauthors found that endoscopic sphincterotomy did not reduce pain any more than did a sham procedure.
In a population-based, matched, retrospective cohort study of 10 390 patients who underwent daytime elective laparoscopic cholecystectomy in Ontario, Canada, Vinden and colleagues study outcomes among patients whose procedures were performed by surgeons who had operated the night before vs surgeons who had not. Zinner and Freischlag comment in a related Editorial.
Sheffield and coauthors investigate the association between intraoperative cholangiography (IOC) use during cholecystectomy and common duct injury in 92 932 Texas Medicare patients aged 66 years or older. In an Editorial, Bilimoria and coauthors discuss the identification and use of the instrumental variable in addressing unmeasured confounders in the estimation of treatment effects.