This meta-analysis compares the association between lowering low-density lipoprotein cholesterol (LDL-C) and cardiovascular risk reduction for statin vs nonstatin therapies that lower LDL-C.
This study uses risk scores from 2 studies to assess their accuracy in predicting cardiovascular events among patients with stable coronary heart disease.
This cohort study investigates the association between urinary sodium excretion and heart failure, myocardial infarction, and stroke in patients with chronic kidney disease.
This randomized clinical trial assesses whether combination naltrexone-bupropion treatment in overweight and obese patients increases major adverse cardiovascular events (MACE) compared with placebo.
This randomized trial investigated the effects of financial incentives paid to physicians, patients, and both on low-density lipoprotein cholesterol levels among patients with high cardiovascular risk.
This randomized trial reports that among men with coronary heart disease, use of a lifestyle-focused text messaging service vs usual care resulted in modest improvement in low-density lipoprotein cholesterol levels and greater improvement in other cardiovascular disease risk factors.
This JAMA Clinical Guidelines Synopsis article summarizes the evidence for physical activity and dietary recommendations in people with cardiovascular risk factors.
Corrales-Medina and coauthors determine whether hospitalization for pneumonia is associated with increased short-term and long-term risk of cardiovascular disease (CVD).
This 40-year observational study reports that sustained, community-wide programs targeting cardiovascular risk factors and behavior changes to improve a Maine county’s population health were associated with reductions in hospitalization and mortality.
This randomized crossover feeding trial reports no improvements in insulin sensitivity, lipid levels, or systolic blood pressure after 5 weeks of following diets with low glycemic index vs high glycemic index of dietary carbohydrate.
McManus and coauthors found that patients with hypertension at risk of cardiovascular disease who were randomly assigned to self-monitor their blood pressure and self-titrate their medication reduced their systolic blood pressure more than did patients who were randomized to the usual care cohort.
Muntner and coauthors report on validation of the atherosclerotic CVD pooled cohort risk equations. In an accompanying Editorial, Krumholz provides persective on the new cholesterol and blood pressure guidelines.
To determine whether adding information on glycated hemoglobin values to conventional cardiovascular risk factors is associated with improvement in prediction of cardiovascular disease (CVD) risk, The Emerging Risk Factors Collaboration analyzed individual-participant data from 73 prospective studies involving 294 998 participants free of diabetes mellitus or CVD at baseline.
Allen and coauthors analyzed data from the prospective CARDIA cohort to identify common blood pressure (BP) trajectories throughout early adulthood and to determine their association with presence of subclinical atherosclerosis during middle age. Sarafidis and Bakris comment in an editorial.