This study describes the development of a pragmatic clinical trial to address questions regarding the use of antibiotics vs appendectomy to treat acute appendicitis.
This study evaluates whether a clinical practice guideline for complicated appendicitis is associated with improved clinical outcomes.
This cohort study examines the effectiveness of patient choice in nonoperative vs surgical management of uncomplicated acute appendicitis in children.
This observational cohort study reports that lengthening of postoperative antibiotic treatment to 5 days was not associated with a reduction in infectious complications after laparoscopic appendectomy for acute complicated appendicitis.
This Viewpoint reviews the study results of and reactions to the Salminen et al acute appendicitis trial and provides recommendations for surgeons who will be confronted by patients questioning whether they need surgery.
Haut proposes that the findings from Salminen et al’s clinical trial are not enough to shift from the use of appendectomy to antibiotics in the treatment of appendicitis.
This study identifies clinical variables associated with the presence of complicated appendicitis.
Mottey and colleagues evaluate whether there is an association between time and perforation after patients present to the hospital.
Kitano and colleagues describe 2 cases of melanoma of the appendix presenting with appendicitis and review their institutional experience with this entity.
Fonseca et al determine whether MR imaging in pregnant patients with suspected appendicitis improves outcomes, minimizes LOS, and lowers hospital charges. They performed a retrospective review at a university tertiary referral center of pregnant patients seen during an 11-year period and followed up through delivery.
Cheong and Emil test the hypothesis that the outcomes of children with appendicitis are better in the Canadian single-payer universal health care system than in the US multipayer system.
Loehrer et al evaluate the impact of Massachusetts health care reform on racial disparities in minimally invasive surgery.
Furman and colleagues undertook a retrospective study to determine the rate of mucinous neoplasms among adults undergoing interval appendectomy.
In a systemic review and meta-analysis, Bhangu et al determine whether delayed primary skin closure of contaminated and dirty abdominal incisions reduces the rate of surgical site infection compared with primary skin closure. See also the Invited Critique by Cohn.