This study uses data from a trial comparing clopidogrel and aspirin vs aspirin alone for preventing stroke in patients with TIA to investigate associations between CYP2C19 status and effects of the drugs.
This analysis of data from Danish administrative registries reports that among patients receiving antithrombotic therapy after myocardial infarction, use of nonsteroidal anti-inflammatory drugs was associated with increased risk of bleeding and thrombotic events.
In a review of the literature on optimal medical therapy after percutaneous coronary intervention
(PCI), Brilakis and coauthors determined that dual antiplatelet therapy remains the standard of
care, with adjustments as needed for patients at high risk for bleeding and those who have coronary