J.-K. Lee and coauthors performed a systematic review and meta-analysis to determine the association between survival and first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors vs chemotherapy among patients with advanced non–small cell lung cancer with wild-type EGFR.
This JAMA Clinical Evidence Synopsis summarizes a Cochrane review of the accuracy of rapid diagnostic tests for detecting P vivax and nonfalciparum malaria in endemic countries.
This randomized trial reports high rates of sustained virologic response in the first part of a open-label study of ombitasvir, paritaprevir (co-dosed with ritonavir), and dasabuvir with ribavirin for 63 patients with hepatitis C virus genotype 1 and human immunodeficiency virus 1 co-infection.
This meta-analysis summarizes evidence about associations between timing of allergenic food introduction during infancy and risk of allergic or autoimmune disease.
This Clinical Evidence Synopsis summarizes a Cochrane review on the efficacy of pharmacological and nonpharmacological interventions for patients with Parkinson disease experiencing fatigue.
This systematic review to support the 2016 update of the US Preventive Services Task Force Recommendation Statement on screening for colorectal cancer summarizes published evidence about the effectiveness of routine screening, accuracy of screening tests and strategies, and potential screening harms.
This randomized clinical trial compares the effects of physical rehabilitation vs usual care on length of stay of ICU patients with acute respiratory failure.
Marrouche and coauthors report the results of the DECAAF study, which was a multicenter assessment of the association of atrial tissue fibrosis identified by delayed enhancement magnetic resonance imaging (MRI) and catheter ablation outcomes in patients with atrial fibrillation.
This simulation study uses Kaiser Permanente patient data to estimate benefits, complications, and costs of colorectal cancer screening stratified by adenoma detection rate and age at initiation.
This study uses National Electronic Injury Surveillance System data to describe trends in adult cycling injuries and related hospital admissions in the United States.